Neonatal hypoxic-ischemic encephalopathy (HIE) takes place in around 1 to 6 out of every 1,000 births. without immediate treatment, infants are at risk of serious brain damage, but fatalities as well. Many infants with HIE are subject to neonatal therapeutic hypothermia, during which, they are placed in a clinical setting through which the temperature is around 33 °C., and generally lasts around three days.
With the type of clinical setting depending upon the infant’s injuries, in most instances, babies are put on a cooling blanket filled with water. Where they are monitored for several days as their metabolic processes slow down.